I was wondering if an option could be added to adjust part spacing based on the direction. For example 5/16" in the Y and 1/4" in the X
This is not possible because the way the part spacing is applied by the algorithms. However, I can think of a way to do this by adjusting the way the parts are drawn but it depends on the nesting settings for rotation being 0 or 180 degrees. I would like to see one of your NestFab jobs to understand and advise better. Of course, we should do this off forum so please could you email our support directly (support AT ...).